why we use acetyl cysteine
The Basics
Acetyl Cysteine (NAC) is a synthetic derivative of the naturally occurring amino acid L-cysteine. It serves as a precursor to glutathione, one of the body's most vital antioxidants, playing a crucial role in neutralising free radicals and reducing oxidative stress. This function is essential in maintaining skin health and preventing premature aging.1
Beyond its antioxidant capabilities, NAC exhibits significant anti-inflammatory effects. By modulating inflammatory pathways, it helps in reducing skin inflammation, which can be beneficial in managing various dermatological conditions.2
NAC has been explored as a therapeutic option for several skin disorders. Its efficacy in conditions characterised by oxidative stress and inflammation underscores its potential as a valuable ingredient in skincare formulations.3
references
- 1 Samuni, Y., Goldstein, S., Dean, O. M., & Berk, M. (2013). The chemistry and biological activities of N-acetylcysteine. Biochimica et Biophysica Acta (BBA) - General Subjects, 1830(8), 4117–4129. doi:10.1016/j.bbagen.2013.04.016 The chemistry and biological activities of N-acetylcysteine.
- 2 Sadowska, A. M., Manuel-Y-Keenoy, B., & De Backer, W. A. (2007). Antioxidant and anti-inflammatory efficacy of NAC in the treatment of COPD: discordant in vitro and in vivo dose-effects: a review. Pulmonary Pharmacology & Therapeutics, 20(1), 9–22. doi:10.1016/j.pupt.2005.12.007 Antioxidant and anti-inflammatory efficacy of NAC in the treatment of COPD: discordant in vitro and in vivo dose-effects: a review.
- 3 Ramdial, P. K., & Motala, A. (2014). The potential uses of N-acetylcysteine in dermatology: a review. Dermatology and Therapy, 4(2), 225–242. doi:10.1007/s13555-014-0064-7 The potential uses of N-acetylcysteine in dermatology: a review.
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