Bisabolol

anti-redness + sensitivity
by cipher skincare published: sep 16, 2022 revised: feb 17, 2026 1 min read
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why we use bisabolol

The Basics

Bisabolol, also known as α-(−)-bisabolol or levomenol, is a natural monocyclic sesquiterpene alcohol predominantly found in German chamomile (Matricaria recutita). This colorless, viscous oil has been utilized in cosmetics for its skin-soothing properties, particularly in calming redness and irritation, making it ideal for sensitive skin types.

Anti-Inflammatory and Antioxidant Properties

Research indicates that bisabolol exhibits significant anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines such as TNF-α and IL-6. In vitro and in vivo studies have demonstrated its ability to reduce skin inflammation, suggesting its potential as a therapeutic agent for inflammatory skin conditions.1

Skin Healing and Antimicrobial Benefits

Beyond its anti-inflammatory action, bisabolol has been shown to possess antimicrobial properties, aiding in the prevention of infection and supporting the skin's natural healing processes. Its application can lead to a reduction in skin irritation and contribute to overall skin health.2

Penetration Enhancement

Notably, bisabolol acts as a penetration enhancer, facilitating the absorption of other active ingredients in topical formulations. This property enhances the efficacy of skincare products by allowing deeper delivery of beneficial compounds into the skin.3

references

  1. 1 Maurya, A. K., Singh, M., Dubey, V., Srivastava, S., Luqman, S., & Bawankule, D. U. (2014). α-(-)-bisabolol reduces pro-inflammatory cytokine production and ameliorates skin inflammation. Current pharmaceutical biotechnology, 15(2), 173–181. doi: 10.2174/1389201015666140528152946 α-(-)-bisabolol reduces pro-inflammatory cytokine production and ameliorates skin inflammation.
  2. 2 Eddin, Lujain & Jha, Niraj & Goyal, Sameer & Agrawal, Yogeeta & Subramanya, Sandeep & Salim, Mims & Ojha, Shreesh. (2022). Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol. Nutrients. 14. 1370. 10.3390/nu14071370. Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol.
  3. 3 Safety Assessment of Bisabolol as Used in Cosmetics. Safety Assessment of Bisabolol as Used in Cosmetics.

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