Why we use Diglucosyl Gallic Acid · Cipher Skincare Skip to main content

Diglucosyl Gallic Acid

Home / Ingredient Glossary / Diglucosyl Gallic Acid
overview

known as Diglucosyl Gallic Acid, Brightenyl, Trihydroxybenzoic acid glucoside (THBG)

source biotechnology

function brightening, antioxidant, photoprotective, soothing, reduce visible hyperpigmentation, redness neutralizer

find it in

Diglucosyl Gallic Acid

Diglucosyl gallic acid is an innovative biotech molecule also known as Trihydroxybenzoic acid glucoside (THBG). It is activated by the skin’s microbiome and acts on seven biological targets to visibly brighten, calm, and protect skin from UV damage.1

Diglucosyl gallic acid (THBG) is an alpha-glucoside derivative of THBA (trihydroxy benzoic acid). Once THBG is applied topically, the skin’s enzymatic microbiota partially converts it to THBA.2 In the skin, THBG and THBA function cooperatively to dramatically brighten skin’s appearance and correct signs of yellowness, sallowness, and redness.3

According to the manufacturer, it works via these 7 modes of action1:

inhibits ROS production (antioxidant)

prevents UV-induced DNA damages (antioxidant)

controls the expression of MITF (brightening)

reduces the expression of PGE2 (reduce visible redness)

controls the Nf-kB pathway (anti-inflammatory)

saturates keratinocytes receptors (brightening)

blocks melanin synthesis even under UV conditions (brightening)

references

[1] Brightenyl® by Givaudan Active Beauty - Personal Care & Cosmetics. (2022). Retrieved 11 September 2022, from https://www.ulprospector.com/en/asia/PersonalCare/Detail/831/592875/Brightenyl

[2] (2022). KERACELL Brightening Serum. Retrieved 12 September 2022, from https://www.truthinaging.com/keracell-anti-aging-brightening-serum

[3] Chajra, H., Redziniak, G., Auriol, D., Schweikert, K., & Lefevre, F. (2015). Trihydroxybenzoic acid glucoside as a global skin color modulator and photo-protectant. Clinical, Cosmetic And Investigational Dermatology, 579. doi: 10.2147/ccid.s93364

Explore More

olive glycerides
Olive Glycerides

Olive Glycerides

Olive Glycerides are a multifunctional emollient ingredient coming from non-edible fractions of olive by-products. This soft, velvety, dry touch oil provides unique synergy…
cipher skincare mail signup xanthan gum
Xanthan Gum

Xanthan Gum

Xanthan gum is a polysaccharide that functions as a natural polymer to help thicken and stabalise products.
peg-100 stearate
PEG-100 Stearate

PEG-100 Stearate

A polyethylene glycol ester of stearic acid, PEG-100 Stearate is a safe and gentle high HLB emulsifier often combined with glyceryl stearate. Together,…
sodium hydroxide caustic soda lye cosmetic ph adjuster
Sodium Hydroxide

Sodium Hydroxide

A pH adjuster that is a strong base, meaning its pH is well above neutral pH 7. It may sound intimidating, but in…