Why we use Ethylhexylglycerin

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why we use ethylhexylglycerin

The Basics

Ethylhexylglycerin is a synthetic glycerin derivative that enhances skin hydration, smoothness, and overall formulation aesthetics. It functions as a humectant, drawing moisture to the skin, while also providing mild antimicrobial benefits that help maintain product integrity. Additionally, it boosts the efficacy of preservatives, reducing the need for higher concentrations of harsher agents.²

How Ethylhexylglycerin Boosts Preservative Efficacy

Ethylhexylglycerin enhances preservative efficacy through multiple mechanisms. Its surfactant-like structure reduces interfacial tension at microbial cell membranes, increasing their permeability. This action facilitates the entry of co-preservatives, such as phenoxyethanol, into microbial cells, leading to enhanced antimicrobial effects. Studies have shown that combining ethylhexylglycerin with phenoxyethanol results in rapid bacterial cell death, membrane disruption, and leakage of cellular contents. This synergistic interaction allows for lower concentrations of traditional preservatives, making formulations more suitable for sensitive skin.²

Furthermore, ethylhexylglycerin creates a biostatic environment that inhibits microbial growth, contributing to overall formulation stability. Its multifunctional nature not only preserves product integrity but also enhances skin feel, making it a valuable component in cosmetic formulations.³

references

1 Cosmetic Ingredient Review Expert Panel. (2012). Final report on the safety assessment of ethylhexylglycerin. Retrieved from Final report on the safety assessment of ethylhexylglycerin.
2 Langsrud, S., Steinhauer, K., Lüthje, S., Weber, K., Goroncy-Bermes, P., & Holck, A. L. (2016). Ethylhexylglycerin Impairs Membrane Integrity and Enhances the Lethal Effect of Phenoxyethanol. PloS one, 11(10), e0165228. doi: 10.1371/journal.pone.0165228 Ethylhexylglycerin Impairs Membrane Integrity and Enhances the Lethal Effect of Phenoxyethanol.
3 Inolex. (n.d.). Lexgard® E. Retrieved from Lexgard® E