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Home / Ingredient Glossary / Glabridin
overview

known as glabridin

source licorice root

function brightening, antioxidant, soothing

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Glabridin

Glabridin is an isoflavonoid isolated from the roots of glycyrrhiza glabra (licorice root). Glabridin brightens by inhibiting activity of melanin-stimulating enzyme tyrosinase and dopachrome tautomerase (TRP-2). Glabridin is a multifunctional active that also posesses antioxidant and soothing anti-inflammatory activity.1 This unique combination of skills ensures efficient, effective brightening of skin’s appearance without irritation.2

references

[1] YOKOTA, T., NISHIO, H., KUBOTA, Y., & MIZOGUCHI, M. (1998). The Inhibitory Effect of Glabridin from Licorice Extracts on Melanogenesis and Inflammation. Pigment Cell Research, 11(6), 355-361. doi: 10.1111/j.1600-0749.1998.tb00494.x

[2] Simmler, C., Pauli, G., & Chen, S. (2013). Phytochemistry and biological properties of glabridin. Fitoterapia, 90, 160-184. doi: 10.1016/j.fitote.2013.07.003

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