Home / Ingredient Glossary / Gluconolactone

Gluconolactone is a polyhydroxy acid (PHA) with more talents than exfoliation alone. It is similar in functionality to alpha hydroxy acids (AHAs) but is considered gentler due to its larger molecular size.1 Like all acids, PHAs stimulate skin’s repair process while lessening the appearance of fine lines, inflammatory imperfections, and age spots. Gluconolactone is an effective chelating agent (binds to metals and helps stabalise formulas) and may also function by scavenging free radicals (antioxidant), thereby protecting skin from some of the damaging effects of UV radiation.2

Gluconolactone doesn’t seem to increase skin’s susceptibility to sunburn as significantly as AHAs, and it may help repair existing cutaneous photodamage.2 It by no means, however, replaces the need to wear broad spectrum sunscreen daily. PHAs are a great option for all skin types and have proven to work well from light to deep skin tones.1

[1] Grimes PE, Green BA, Wildnauer RH, Edison BL. The use of polyhydroxy acids (PHAs) in photoaged skin. Cutis. 2004 Feb;73(2 Suppl):3-13.
[2] Bernstein, E.F., Brown, D.B., Schwartz, M.D., Kaidbey, K. and Ksenzenko, S.M. (2004), The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoaging. Dermatologic Surgery, 30: 189-196. doi:10.1111/j.1524-4725.2004.30060.x


Products with Gluconolactone

  • Cloud Melt

    Balancing Hybrid Cleanser: calm + clarify

    An indulgent daily ritual to perfectly prep the skin. Gently clarify, soothe redness and sensitivity, and delicately refine texture with this impurity dissolving balm and nourishing gel cleanser in one.

  • Ctrl Z

    multi-corrective overnight facial: resurface + renew

    An advanced resurfacing treatment to dynamically recondition skin’s appearance. An intelligent blend of direct acid, enzyme, and non-acid exfoliants soften visible blemishes, hyperpigmented spots, pores, and texture. Novel actives add supple volume, boost luminosity, and support a resilient microbiome for facial-like results overnight.


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