why we use palmitic acid
The Basics
Palmitic acid is a saturated fatty acid that plays a key role in maintaining skin barrier integrity and hydration. As one of the most abundant fatty acids in the stratum corneum, it contributes to the structural composition of the skin’s lipid matrix, reinforcing barrier function and reducing transepidermal water loss (TEWL). This helps to keep skin hydrated and protected from external irritants.1
In addition to its barrier-enhancing effects, palmitic acid provides a rich, creamy texture to skincare formulations, improving product spreadability and sensory appeal. It acts as an occlusive agent, forming a lightweight protective layer on the skin’s surface to prevent moisture loss. While beneficial for dry and mature skin, its heavier nature may not be ideal for acne-prone individuals when used in high concentrations.2
Palmitic acid is also used as a co-emulsifier in formulations, helping to stabilise oil-in-water emulsions and improve the longevity of skincare products. Its ability to enhance formulation stability makes it a key component in creams, lotions, and other rich-textured products designed to support long-lasting skin hydration.3
references
- 1 Wertz PW. Lipids and the Permeability and Antimicrobial Barriers of the Skin. J Lipids. 2018 Sep 2;2018:5954034. doi: 10.1155/2018/5954034. PMID: 30245886; PMCID: PMC6139190. Lipids and the Permeability and Antimicrobial Barriers of the Skin.
- 2 Elias PM. Stratum corneum defensive functions: an integrated view. J Invest Dermatol. 2005 Aug;125(2):183-200. doi: 10.1111/j.0022-202X.2005.23668.x. PMID: 16098026. Stratum corneum defensive functions: an integrated view.
- 3 Lodén M. The clinical benefit of moisturizers. J Eur Acad Dermatol Venereol. 2005 Nov;19(6):672-88; quiz 686-7. doi: 10.1111/j.1468-3083.2005.01326.x. PMID: 16268870. The clinical benefit of moisturizers.
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