Palmitoyl tripeptide-38 is a matrikine-mimetic compound that regulates cell activity, wound repair and collagen tissue remodeling. It stimulates six major constituents of the skin matrix and the dermal-epidermal junction to plump fine lines and boost skin repair.
Topical treatments containing this peptide have shown a significant increase in dermal density and elasticity.1 First visible wrinkle smoothing results were achieved in as little as one week.1
The six avenues this peptide addresses include:
① Collagen I – The major component of the dermis.
② Collagen III – Collagen produced in the earliest phases of wound healing, before type I collagen synthesis initiation. It is mostly found in elastic tissues, including the skin, muscles and blood vessels, and it diminishes with age in favor of collagen I.
③ Collagen IV – Has wound healing stimulation properties. It interacts with keratinocytes, which induce epidermal cell proliferation immediately after a skin injury.
④ Fibronectin – A glycoprotein that appears to have a role in the stimulation and acceleration of in vivo tissue repair.
⑤ Hyaluronic acid – Known for facilitating wound repair, hyaluronic acid is thought to improve skin moisture and elasticity. Hyaluronic acid can promote the delivery of active ingredients to the inner layers of the skin and has free radical scavenging properties.
⑥ Laminin-5 – Alongside collagens and proteoglycans, laminins are important components of the basement membrane. Laminin-5 anchors the epidermis to the dermis. It also regulates keratinocyte migration, facilitating the healing of injured epidermis.
 Schagen, S. (2017). Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics, 4(2), 16. doi: 10.3390/cosmetics4020016
Products with Palmitoyl Tripeptide-38
- A$50.00 – A$148.0050ml10ml
illuminating anti-stress treatment: brighten + mend
A soft, lightweight treatment to target the appearance of redness, dullness, and skin stress. Protect and soothe skin from the visible effects of free radical exposure, inflammatory response, or a compromised skin barrier. multiphasic actives restore vibrancy, lift tired skin, brighten the appearance of dark circles and enhance overall luminosity.
- A$52.00 – A$165.0050ml10ml
holistic tone balancing treatment: revitalize + perfect
An innovative approach to pigment correction delivering holistic skin balance and unprecedented radiance simultaneously. Multifunctional brighteners visibly lift discolorations, cellular repair agents target fine lines and redness, and active botanicals support resilience and vitality. A transformative treatment for skin that looks healthy, vibrant, and restored.
- A$58.00 – A$195.0050ml10ml
multi-corrective overnight facial: resurface + renew
An advanced resurfacing treatment to dynamically recondition skin’s appearance. An intelligent blend of direct acid, enzyme, and non-acid exfoliants soften visible blemishes, hyperpigmented spots, pores, and texture. Novel actives add supple volume, boost luminosity, and support a resilient microbiome for facial-like results overnight.