Why we use Piroctone Olamine

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A hero of scalp care

Piroctone Olamine is a synthetic antifungal agent renowned for its efficacy in addressing scalp concerns, particularly in leave-on treatments. Its primary mechanism involves inhibiting the growth of Malassezia species, fungi implicated in dandruff and seborrheic dermatitis. By restoring the scalp's natural balance, it effectively reduces flaking and itchiness.

Beyond its antifungal properties, Piroctone Olamine has demonstrated significant benefits in reducing hair shedding. A randomized, double-blind, placebo-controlled clinical study revealed that scalp application of Piroctone Olamine over eight weeks led to a statistically significant increase in hair count compared to placebo. This effect is attributed to its antioxidant activity, which mitigates oxidative stress on the scalp, thereby improving hair retention.

In leave-on scalp treatments, Piroctone Olamine offers prolonged contact time, enhancing its efficacy in combating fungal overgrowth and supporting scalp health. Its incorporation into such formulations ensures continuous activity against dandruff-causing agents, providing relief from associated symptoms and promoting a healthier scalp environment.

references

1 Davis MG, Piliang MP, Bergfeld WF, Caterino TL, Fisher BK, Sacha JP, Carr GJ, Moulton LT, Whittenbarger DJ, Punyani S, Schwartz JR. Scalp application of the antioxidant piroctone olamine reduces hair shedding in an 8-week randomized, double-blind, placebo-controlled clinical study. Int J Cosmet Sci. 2021 Nov;43 Suppl 1:S26-S33. doi: 10.1111/ics.12737. PMID: 34424549.Scalp application of the antioxidant piroctone olamine reduces hair shedding in an 8-week randomized, double-blind, placebo-controlled clinical study.