Sodium Chondroitin Sulfate
Sodium Chondroitin Sulfate is a glycosaminoglycan that functions as a powerful humectant. It’s part of the skin’s dermis and is responsible for keeping skin bouncy and hydrated—just like its relative hyaluronic acid. In our formulas, sodium chondroitin sulfate makes up one component of a rapid delivery skin plumping system. In this system, sodium chondroitin sulfate combines with vegan collagen, hyaluronic acid, and phospholipids to noticably lift skin and plump the appearance of fine lines and wrinkles.
To create this skin plumping system, vegan collagen is derived through biotechnology from saccharomyces cerevisiae yeast. The dehydrated collagen is then loaded into a nourishing phospholipid base along with hyaluronic acid and chondroitin. This active-loaded delivery system strives to build a “scaffold” in the skin mimicking its own collegen structure. This biomimetic structure provides support and noticable volume instantly.1
The dehydrated nature of the nanoparticles allows them to penetrate skin quickly and “swell rapidly forming a reconstituted human tissue matrix” in the skin.2 “The chondroitin sulfate and hyaluronic acid crosslink with the collagen, giving the matrix a distinct 3-Dimensional structure; creating a firm, supple aesthetic coupled with the sensation of rapid firming.”
NanoVesicular delivery systems vs. Liposomes
They have some things in common, but the two differ slightly.
Like the system we’ve discussed here, liposomes are also used to aid in delivery of actives. In order to form liposomes, actives are loaded inside phospholipid spheres. These fragile spheres require suspension in a aqueous base in order to remain intact.
This system differs from liposomal systems in that it is water-free. It goes by the name NanoVector or NanoVesicular3, which simply means an active loaded in a nanosized pocket. These systems disperse dehydrated nanoparticles in a phospholipid base without the aqueous input, thereby optimizing their application in anhydrous (water-free) systems.
 Wang, W., Zhang, M., Lu, W., Zhang, X., Ma, D., & Rong, X. et al. (2010). Cross-linked Collagen–Chondroitin Sulfate–Hyaluronic Acid Imitating Extracellular Matrix as Scaffold for Dermal Tissue Engineering. Tissue Engineering Part C: Methods, 16(2), 269-279. doi: 10.1089/ten.tec.2009.0161
 FSS NANOVESICULAR SYSTEM P3. (2022). Retrieved 26 September 2022, from https://www.formulatorsampleshop.com/fss-nanovesicular-system-p3.html
 AC™ NanoVector System P3. Retrieved 26 September 2022, from https://www.knowde.com/stores/active-concepts-llc/products/ac-nanovector-system-p3/