why we use superoxide dismutase
The Basics
Superoxide Dismutase (SOD) is a critical enzyme present in all living cells, serving as a primary defense against oxidative stress by catalysing the dismutation of superoxide radicals into oxygen and hydrogen peroxide. This enzymatic action is essential for maintaining cellular integrity and preventing damage induced by reactive oxygen species (ROS).1
A Unique Mode of Action
SOD works by catalysing the conversion of superoxide radicals into molecular oxygen and hydrogen peroxide. Unlike standard antioxidants, enzymatic SOD is not depleted during this neutralisation process, allowing it to continuously protect the skin from oxidative stress.1 This unique property makes SOD one of the most efficient and sustainable antioxidants available in skincare.
What Superoxide Dismutase can do for skin
antioxidant
In dermatological applications, SOD is esteemed for its potent antioxidant capabilities. By neutralising superoxide radicals, SOD mitigates oxidative damage to skin cells, thereby preserving skin structure and function. Research indicates that SOD can prevent the degradation of collagen fibres, a process often accelerated by oxidative stress, thus maintaining skin elasticity and reducing the appearance of fine lines and wrinkles.2
Soothing
Furthermore, SOD exhibits skin-soothing properties, which can alleviate redness and irritation. Its ability to modulate inflammatory responses supports calmer, more even-toned skin.3
Protective
Additionally, SOD enhances the skin’s resilience against environmental stressors, such as ultraviolet (UV) radiation and pollution. By bolstering the skin’s natural antioxidant defence mechanisms, SOD helps protect against visible signs of skin stress, contributing to a more vibrant and healthy complexion.3
references
- 1 Perry, J. J. P., Shin, D. S., Getzoff, E. D., & Tainer, J. A. (2010). The structural biochemistry of the superoxide dismutases. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1804(2), 245–262. doi: 10.1016/j.bbapap.2009.11.004
- 2 Lee, M. J., Agrahari, G., Kim, H. Y., An, E. J., Chun, K. H., Kang, H., Kim, Y. S., Bang, C. W., Tak, L. J., & Kim, T. Y. (2021). Extracellular superoxide dismutase prevents skin aging by promoting collagen production through the activation of AMPK and Nrf2/HO-1 cascades. Journal of Investigative Dermatology, 141(10), 2344–2353.e7. doi: 10.1016/j.jid.2021.02.757
- 3 Zheng, M., Liu, Y., Zhang, G., Yang, Z., Xu, W., & Chen, Q. (2023). The Applications and Mechanisms of Superoxide Dismutase in Medicine, Food, and Cosmetics. Antioxidants, 12(9), 1675. doi 10.3390/antiox12091675
explore more
-
Glabridin
Glabridin is an isoflavonoid isolated from the roots of glycyrrhiza glabra (licorice root). This multifunctional active is a…
read more → -
Dimethyl Isosorbide
A biobased solvent and carrier. It solubilizes difficult to dissolve ingredients (like salicylic acid) without allowing them to…
read more → -
Xylitol
A natural sugar alcohol derived from plants. This efficient saccharide humectant is part of a trio of tack-free…
read more → -
Xanthan Gum
Xanthan gum is a polysaccharide that functions as a natural polymer to help thicken and stabalise products.
read more → -
Phospholipids
Phospholipids are nourishing skin-identical emollients with water binding properties. They make up about 75% of the cell membranes…
read more → -
Glyceryl Oleate Citrate
Glyceryl oleate citrate is an ester of glycerin that functions as an emulsifier and emollient. It helps stabilise…
read more →
