Xylitylglucoside

hydrating
by cipher skincare published: sep 21, 2022 revised: feb 17, 2026 1 min read
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why we use xylitylglucoside

Advanced Sugar-Derived Hydration

Xylitylglucoside is a naturally derived compound made from the plant sugars xylitol and glucose. It plays a key role in maintaining skin hydration and reinforcing the skin barrier. As part of a powerful trio with anhydroxylitol and xylitol, it works to optimise the skin’s water reserves, boost moisture retention, and protect against dehydration.

How Xylitylglucoside Works: Enhancing Hydration and Barrier Function

Xylitylglucoside improves skin health through multiple biological pathways:1

  • Boosts Natural Moisture Reserves: It increases the production of natural moisturising factors (NMFs), such as hyaluronic acid and chondroitin sulfate. These molecules bind water within the skin, ensuring deep and long-lasting hydration.
  • Strengthens the Skin Barrier: By stimulating the production of ceramides and cholesterol, xylitylglucoside helps reinforce the lipid barrier. This added protection reduces transepidermal water loss (TEWL) and defends against environmental stressors.
  • Improves Water Circulation: It enhances the expression of aquaporin-3, a protein responsible for water movement between skin layers. As a result, hydration is distributed more evenly across the epidermis.

Proven Benefits for Skin Hydration

Research shows that skincare formulas containing xylitylglucoside, combined with anhydroxylitol and xylitol, can significantly increase moisture levels while strengthening the skin barrier. Clinical studies confirm that regular use leads to improved hydration, less dryness, and a smoother, more resilient complexion.1

Ideal for All Skin Types

Xylitylglucoside provides deep hydration without heaviness, making it ideal for all skin types, including dry and sensitive skin. Its ability to enhance the skin’s moisture balance and fortify the barrier makes it a valuable addition to formulations designed to support healthy, hydrated, and well-protected skin.

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