Cipher Skincare Night Shift holistic tone balancing treatment hyperpigmentation skin strengthening redness
Cipher Skincare Night Shift holistic tone balancing treatment hyperpigmentation skin strengthening redness
hyperpigmentation treatment Cipher Skincare Night Shift Holistic Tone Balancing Treatment Texture

Night Shift

Resilience-Building Brightening Treatment

59 reviews
US$128
A resilience-first brightening treatment powered by DNA-repair enzymes. A holistic complex revitalises skin while targeted actives brighten uneven tone, rebalance oiliness, and diminish the look of blemishes without compromising barrier integrity. Over time, tolerance builds, reactivity eases, texture smooths, and skin looks calm, even, and luminous.

Resilience-Building Brightening Treatment

equiv. US$77 per 30ml (industry std.)

A resilience-first brightening treatment powered by DNA-repair enzymes. A holistic complex revitalises skin while targeted actives brighten uneven tone, rebalance oiliness, and diminish the look of blemishes without compromising barrier integrity. Over time, tolerance builds, reactivity eases, texture smooths, and skin looks calm, even, and luminous.

Bright skin, meet strong skin.

A science-backed treatment designed to dynamically balance skin tone while fortifying skin integrity. Simultaneously addressing hyperpigmentation and supporting rhythmic cellular repair, this formula helps diminish pigmented spots, restore vibrancy, and foster long-term resilience.

Key Actives DNA Repair Enzymes, Potassium Azeloyl Diglycinate, Alpha Arbutin, Niacinamide, Triple Licorice Root Complex, Aรงaรญ + Hemp Seed, Madecassoside, Hydration Complex, Prebiotic Microalgae, Beta Glucan, Panthenol, Palmitoyl Tripeptide-38
pH 6.0-6.5
Fragrance none
Skin Type All [esp. lacklustre, hyperpigmented, redness-prone]
Frequency 1-2x/day
When [AM/PM] EITHER [especially PM]
Vegan โœ“
Texture
light rich
7

How It Works

hyperpigmentation treatment Cipher Skincare Night Shift Holistic Tone Balancing Treatment Texture
[ 01 / 04 ]

Powerful Pigmentation Correction

key actives Alpha Arbutin / Glabridin / Potassium Azeloyl Diglycinate / Niacinamide

Potassium azeloyl diglycinate and niacinamide form a functional duo that gently reduces visible hyperpigmentation while being kind to sensitive skin. This is further enhanced by alpha arbutin and a pure-grade glabridin extract from licorice root, which work synergistically to brighten the look of stubborn spots and promote an even skin tone. Together, these potent actives effectively target discolourations without irritation.

Comprehensive Redness Relief

key actives Glycyrrhizinic Acid / Licochalcone A / Potassium Azeloyl Diglycinate / Niacinamide

Beyond pigmentation, potassium azeloyl diglycinate and niacinamide also work to reduce visible redness and strengthen skin prone to flushing. A triple licorice root complex offers a comprehensive approach: glabridin lightens spots, glycyrrhizinic acid provides anti-inflammatory benefits, and licochalcone A soothes irritation and visible redness. Restorative beta glucan supports barrier functionality and calms stressed skin, leaving it balanced and comfortable.

Holistic Cellular Repair

key actives DNA Repair Enzymes: UV Damage Endonuclease (UVDE) / Oxoguanine Glycosylase (OGG1) / Thioredoxin (TRX)

Every day, our skin is exposed to UV radiation, environmental pollutants, and internal stressors, leading to cumulative cellular damage that accelerates aging. Night Shift addresses this by incorporating a triple-enzyme DNA repair complex derived from Icelandic arctic microalgae. This advanced liposomal delivery system delivers energy-independent, night-active enzymes that enhance the skin’s natural repair processes during rest. By targeting oxidative and UV-induced DNA damage at the cellular level, it promotes visible improvements in radiance, firmness, and texture within as little as 10 days. Regular use helps revitalize the skin, making it more resilient against future stressors.

Barrier Fortification and Deep Nourishment

key actives Beta Glucan / Prebiotic Microalgae / Madecassoside / Acai Berry Oil / Hemp Seed Oil / Palmitoyl Tripeptide-38

Night Shift fortifies the skinโ€™s barrier by combining prebiotic chlorella microalgae, which fosters a balanced microbiome, with potent restorative actives. Madecassoside and beta glucan work in synergy to calm irritation and promote repair, while palmitoyl tripeptide-38 supports collagen production, enhancing elasticity and softening fine lines. Nutrient-dense acai berry and hemp seed oils, abundant in omega fatty acids, deeply hydrate and provide a soft, emollient finish.

Key Ingredients

Triple-Enzyme DNA Repair Complex
Potassium Azeloyl Diglycinate
Alpha Arbutin
Niacinamide
Triple Licorice Root Complex
Madecassoside
Palmitoyl Tripeptide-38
Hemp Seed Oil
Aรงaรญ Fruit Oil
Prebiotic Green Microalgae
Panthenol
Beta Glucan
[ 01 / 12 ]

Triple-Enzyme DNA Repair Complex

Hyperpigmentation Anti-Redness + Sensitivity Anti-Wrinkle + Laxity Antioxidant Barrier Support
Liposome encapsulated enzymes (UVDE, OGG1, and TRX) derived from Icelandic arctic microalgae. They target cellular DNA repair and antioxidant systems to boost radiance, firmness, and smoothness in as little as 10 days.

Potassium Azeloyl Diglycinate

Hyperpigmentation Anti-Redness + Sensitivity Anti-Wrinkle + Laxity Hydrating Acne-Prone
Water-soluble derivative of azeleic acid with many skin benefits. It has soothing effects, visibly brightens, normalizes sebum, reduces visible redness, and boosts hydration levels.

Alpha Arbutin

Hyperpigmentation Antioxidant
Skin-brightening agent that inhibits activity of the enzyme tyrosinase to gently correct the appearance of hyperpigmented marks and balance skin tone.

Niacinamide

Hyperpigmentation Anti-Redness + Sensitivity Anti-Wrinkle + Laxity Antioxidant Hydrating Barrier Support Acne-Prone
Multifunctinal hero known to visibly brighten the skin, reduce the appearance of pores, support healthy skin barrier function, and give skin a smooth, clear, vibrant look.

Triple Licorice Root Complex

Glabridin / Glycyrrhetinic Acid / Licochalcone A

Hyperpigmentation Anti-Redness + Sensitivity Antioxidant Barrier Support
Three actives, two licorice species. Glabridin (98% pure, G. glabra) inhibits tyrosinase โ€” the enzyme behind dark spots. Glycyrrhetinic acid (concentrated whole root) soothes visible redness. Licochalcone A (G. inflata, 20% standardised) modulates NF-ฮบB and NLRP3 pathways while activating Nrf2 antioxidant enzymes โ€” calming reactive skin and defending against environmental damage.

Madecassoside

Hyperpigmentation Anti-Redness + Sensitivity Anti-Wrinkle + Laxity Antioxidant
From the Centella asiatica plant, this calming soother promotes smooth skin while mitigating visible redness. It also reduces itching and burning sensations.

Palmitoyl Tripeptide-38

Anti-Wrinkle + Laxity Hydrating
Skin-mimicking peptide that stimulates six major skin components (collagen I, III, IV, fibronectin, hyaluronic acid, and laminin 5) to noticeably smooth fine lines, support healthy collagen stores, and boost elasticity.

Hemp Seed Oil

Anti-Redness + Sensitivity Anti-Wrinkle + Laxity Barrier Support
Green-yellow-hued emollient rich in linoleic and linolenic acids, terpenes, terpenoids, and flavonoids. This exceptionally soothing lipid is perfect for skins prone to sensitivity, acne, and other ailments.

Aรงaรญ Fruit Oil

Anti-Redness + Sensitivity Antioxidant Barrier Support
Gorgeously green-hued emollient packed with fatty acids, vitamins, minerals, anthocyanins, and polyphenols that effectively restore skin elasticity and smoothness.

Prebiotic Green Microalgae

Anti-Redness + Sensitivity Anti-Wrinkle + Laxity Antioxidant Acne-Prone
A blend of microalgae barrier polysaccharides upcycled fromย Haematococcus pluvialis waste. Prebiotic activity brings a balanced skin state and growth-factor-like performance supports wound healing.

Panthenol

Anti-Redness + Sensitivity Hydrating Barrier Support
Nourishing vitamin that stimulates vital skin lipids that aid in optimizing skin barrier function. It promotes wound healing, boosts hydration, and reduces sensations of itching and irritation.

Beta Glucan

Anti-Redness + Sensitivity Antioxidant Barrier Support
Soothing polysaccharide with remarkable wound healing abilities. It helps to repair, hydrate, and smooth skin's appearance while calming the look of irritated skin reactions.
Full Ingredients List (INCI)

Aqua, Niacinamide, Potassium Azeloyl Diglycinate, Isodecyl Neopentanoate, Alpha Arbutin, Cannabis Sativa (Hemp) Seed Oil, Glycereth-26, Lactobacillus/Eriodictyon Californicum (Yerba Santa) Ferment Extract, PEG/PPG-14/7 Dimethyl Ether, Undecane, Propanediol, Panthenol, Glyceryl Stearate, PEG-100 Stearate, Euterpe Oleracea (Acai) Fruit Oil, Tridecane, Hydroxypropyl Starch Phosphate, plankton extract, Glycyrrhiza Glabra (Licorice) Root Extract, Glycyrrhiza Inflata (Licorice) Root Extract, Chlorella Vulgaris (Microalgae) Extract, Glycerin, Palmitoyl Tripeptide-38, Xylitylglucoside, Glabridin, Madecassoside, Beta Glucan, Anhydroxylitol, Xylitol, Ethyl Oleate, Tocopherol, Bisabolol, Zingiber Officinale (Ginger) Root Extract, Glyceryl Oleate Citrate, Cetyl Alcohol, Triolein, Glyceryl Dioleate, Hydroxyacetophenone, Caprylic/Capric Triglyceride, Lecithin, Polyacrylate Crosspolymer-6, Hydroxypropyl Cyclodextrin, Lauroyl Lysine, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin, Lactic Acid

We are dedicated to providing the most innovative, functional formulations possible and ingredient lists are occasionally updated to reflect this.

How To Use

The Ritual

Apply two to four pumps to clean face, neck, and eye contour. Gently massage to absorb.

Perfect as a standalone, multitasking treatment or layered as desired. May also be used during the day. For best results, use at least once per day, wear sunscreen, and limit sun exposure.

FAQ

+ [FAQ-01] What are DNA repair enzymes?

DNA repair enzymes are specialised proteins that support the skinโ€™s natural ability to repair damage at the cellular level. They target oxidative and environmental stressors, such as UV exposure and pollution, which can lead to visible signs of ageing, uneven tone, and loss of firmness. By addressing DNA damage directly, these enzymes help improve skin health and resilience over time.
In Night Shift, the DNA repair complex features three advanced enzymes derived from the microalgae Haematococcus pluvialis and Chlorella vulgaris. Encapsulated in a lecithin-based delivery system for optimal absorption, these enzymes function effectively overnight to amplify repair processes:

  1. UV Damage Endonuclease (UVDE): Identifies and initiates the repair of UV-induced DNA damage by cleaving damaged strands, supporting the skinโ€™s natural repair process.
  2. Oxoguanine Glycosylase (OGG1): Plays a critical role in repairing oxidative DNA damage by detecting and removing oxidised bases, reducing cellular stress and improving overall skin integrity.
  3. Thioredoxin (TRX): A powerful antioxidant enzyme that protects cells from oxidative damage by maintaining their redox balance and reducing protein damage.

Together, these enzymes support cellular repair and promote smoother, firmer, and more resilient skin over time. For a deeper dive into the enzymes in Night Shift, visit this page.

+ [FAQ-02] What makes Night Shift's licorice root complex special?

Not all plant extracts are created equal. Night Shiftโ€™s licorice root complex features three highly specialised extracts, each derived from specific components of licorice plants:

  1. Glabridin (Glycyrrhiza glabra): Inhibits tyrosinase, effectively reducing visible pigmentation and promoting a more uniform skin tone.
  2. Glycyrrhizinic Acid (Glycyrrhiza glabra): An anti-inflammatory compound that soothes irritation, calms redness, and strengthens the skin barrier.
  3. Licochalcone A (Glycyrrhiza inflata): A bioactive compound with potent antioxidant properties that reduces visible redness and reinforces the skinโ€™s natural defences.

Together, this triple licorice root complex offers unparalleled benefits for pigmentation correction, redness relief, and overall skin balance.

+ [FAQ-03] What makes Night Shift unique?

Night Shift combines advanced pigmentation correctors, redness neutralisers, and a triple-enzyme DNA repair complex to deliver visible results without compromising skinโ€™s integrity. Its multifunctional approach ensures comprehensive care for a brighter, more resilient complexion.

+ [FAQ-04] Can Night Shift help with hyperpigmentation?

Yes, Night Shift is specifically designed to address hyperpigmentation through a multi-faceted approach. It combines potent actives like potassium azeloyl diglycinate, alpha arbutin, glabridin, and niacinamide to target the appearance of discolouration and uneven tone. These ingredients work synergistically to minimise hyperpigmented spots while brightening and refining skin tone over time.

+ [FAQ-05] Can Night Shift help with redness?

Yes, potassium azeloyl diglycinate, niacinamide, and a triple licorice root complex work together to visibly reduce redness, soothe irritation, and strengthen skin prone to flushing. These actives promote a balanced, calm complexion over time.

+ [FAQ-06] How long will it take to see results?

Improvements in hydration and radiance can be noticed within days. Significant changes in the appearance of hyperpigmentation, redness, and texture typically appear after consistent use for 12+ weeks.

+ [FAQ-07] Is Night Shift a serum or a moisturiser?

Night Shift is both. This innovative serum-moisturiser hybrid is loaded with the potent actives of a treatment serum but provides the nourishing benefits of a moisturiser. Ideal as a stand-alone treatment for oily skin, while dry skin types may layer it with a rich moisturiser or occlusive over top.

+ [FAQ-08] Can I use Night Shift during the day?

Yes, Night Shiftโ€™s antioxidant benefits make it a versatile addition to daytime routines. Whether used day or night, it provides restorative and protective benefits for the skin.

+ [FAQ-09] Is Night Shift suitable for sensitive skin?

Yes, Night Shift is formulated with soothing ingredients like madecassoside, beta glucan, and panthenol to minimise irritation while providing effective results. These actives work to calm redness and strengthen the skin barrier, making it ideal for sensitive skin. Patch testing is recommended for very reactive skin types.

+ [FAQ-10] Can I layer Night Shift with other actives?

Yes, one of Night Shift’s unique strengths is its flexibility. It works brilliantly on its own or with other skincare products and can be paired with additional actives. Its resilience-building properties make it particularly effective alongside retinoids to enhance results. For sensitive skin, patch test and introduce strong actives gradually.

+ [FAQ-11] Who is Night Shift best for?

Night Shift is ideal for anyone targeting hyperpigmentation, redness, or uneven tone while seeking a product that supports long-term resilience and skin health. Its gentle yet effective formula suits all skin types, including sensitive skin.

+ [FAQ-12] Does Night Shift work on all skin tones?

Absolutely. Night Shiftโ€™s advanced formula is designed to be effective and safe for all skin tones, addressing pigmentation, redness, and texture concerns universally.

Reviews

4.86 out of 5
based on 59 reports
+ View Rating Breakdown
5
52
4
6
3
1
2
0
1
0
1-3 of 59 reviews
  1. Report 01
    Nearing the end of my first bottle I can now say this is by far my favorite skin care product. Ever. I've always had PIH due to acne scarring, and then more recently started developing redness around my mouth that...
    (4) (0)
    TJ ยท Verified
  2. Report 02
    Great improvement to my skin, I have never seen my skin glow right after a wash. I am very satisfied and impressed with the result in month use of it.
    (5) (1)
    ROLAND MANURUNG ยท Verified
  3. Report 03
    Love the thoughtful combination of actives, rare to see so many action-packed actives all in the same productโ€”especially in such a lightweight texture! The only thing I donโ€™t love is it leaves me super dewy even if I stick to...
    (2) (0)
    Mark S. ยท Verified
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