Why we use Anhydroxylitol

↓ skip to summary

Advanced Sugar-Derived Hydration

Anhydroxylitol, a dehydrated derivative of the natural sugar xylitol, plays a pivotal role in enhancing skin hydration and barrier function. As part of a synergistic trio with xylitylglucoside and xylitol, it optimises the skin's water reserves, promotes moisture retention, and fortifies the skin's natural defenses against dehydration.

Mechanism of Action: Enhancing Skin Hydration and Barrier Function

Anhydroxylitol exerts its effects through multiple biological pathways:¹

Stimulation of Essential Lipids and Proteins: It promotes the synthesis of ceramides, cholesterol, and proteins crucial for maintaining the stratum corneum's integrity, thereby reinforcing the skin's barrier function.
Optimisation of Water Circulation: By enhancing the expression of aquaporin-3, a protein that facilitates water transport between skin layers, anhydroxylitol ensures efficient hydration distribution throughout the epidermis.
Augmentation of Natural Moisturising Factors (NMFs): It boosts the production of hyaluronic acid and chondroitin sulfate, key components of the skin's extracellular matrix, which bind water and maintain tissue hydration.

Clinical Evidence Supporting Anhydroxylitol's Efficacy

Studies have demonstrated that formulations containing anhydroxylitol, xylitylglucoside, and xylitol significantly improve skin hydration levels and barrier function. Participants experienced increased moisture retention and reduced transepidermal water loss (TEWL), leading to a more resilient and supple complexion.¹

Ideal for All Skin Types

Due to its gentle yet effective hydrating properties, anhydroxylitol is suitable for all skin types, including sensitive and dry skin. Its ability to enhance the skin's natural moisture retention mechanisms makes it a valuable addition to skincare formulations aimed at improving overall skin health and appearance.

references

1 Garcia, C., Valin, E., Hernandez, E., Kern, C., Roso, A., Garcia, C., Valin, E., Hernandez, E., Kern, C., & Roso, A. (2023). Effect of a Simple Sugar-based Ingredient on Skin Moisturization: Biological Mode of Action and Clinical Effects. Asian Journal of Beauty and Cosmetology, 21(1), 13–27. https://doi.org/10.20402/ajbc.2022.0051 Effect of a Simple Sugar-based Ingredient on Skin Moisturization: Biological Mode of Action and Clinical Effects.
2 AQUAXYL - SEPPIC - Anhydroxylitol - Anti-Aging Agent - COSMOS. (2025). Knowde. 23 Feb 2025 from AQUAXYL - SEPPIC - Anhydroxylitol - Anti-Aging Agent - COSMOS.